Abstract
BACKGROUND CONTEXT
Anterior Lumbar Interbody Fusion (ALIF) is a lumbar arthrodesis technique via an anterior
approach that is less invasive than the posterior approaches. However, it is associated
with specific pain in the abdominal wall.
PURPOSE
The objective of this study was to determine whether performing a bilateral ultrasound-guided
Transversus Abdominis Plane (TAP) block allows a reduction in morphine consumption
in the first 24 hours after surgery.
STUDY DESIGN
This study is a prospective single-center, randomized, double-blind study.
PATIENT SAMPLE
Patients undergoing ALIF surgery were included and randomized into two groups. Both
groups received a TAP block performed at the end of surgery with either ropivacaine
or placebo.
OUTCOME MEASURES
The primary outcome measure was morphine consumption in the first 24 hours. The main
secondary outcomes were immediate postoperative pain and opioid-related side effects.
METHODS
Intra- and postoperative anesthesia and analgesia protocols where standardized. A
bilateral ultrasound-guided TAP block was performed with 75 mg (in 15 mL) of ropivacaine
per side or isotonic saline serum depending on their assignment group.
RESULTS
Forty-two patients were included in the study (21 per group). Morphine consumption
at 24 hours (28 mg [18–35] in the ropivacaine group versus 25 mg [19–37] in the placebo
group (p=.503)) were not significantly different between the two groups.
CONCLUSION
TAP block with ropivacaine or placebo provided a similar postoperative analgesia when
associated with a multimodal analgesia protocol for ALIF.
Keywords
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Article info
Publication history
Published online: April 07, 2023
Accepted:
March 22,
2023
Received in revised form:
February 7,
2023
Received:
October 5,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
FDA device/drug status: Not applicable.
Author disclosures: AC: Grant: APiciL (C, Paid directly to institution). AS: Grant: APiciL (C, Paid directly to institution). AB: Grant: APiciL (C, Paid directly to institution). MR: Grant: APiciL (C, Paid directly to institution). HB: Grant: APiciL (C, Paid directly to institution).
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