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Research Letter| Volume 23, ISSUE 6, P885-887, June 2023

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Preoperative frailty and 30-day mortality after surgery for type II odontoid fracture: a retrospective observational analysis of a large multicenter surgical registry

  • Kavelin Rumalla
    Affiliations
    Department of Neurosurgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA

    Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, NM 87131, USA
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  • Syed Faraz Kazim
    Affiliations
    Department of Neurosurgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA

    Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, NM 87131, USA
    Search for articles by this author
  • Priyanka Jain
    Affiliations
    Department of Neurosurgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA
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  • Rohini G. McKee
    Affiliations
    Department of Surgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA
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  • Meic H. Schmidt
    Affiliations
    Department of Neurosurgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA

    Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, NM 87131, USA
    Search for articles by this author
  • Christian A. Bowers
    Correspondence
    Corresponding author. Christian A. Bowers, MD, Department of Neurosurgery, University of New Mexico Health Sciences Center, 1 University New Mexico, MSC10 5615, Albuquerque, NM, 81731, USA. Tel.: (505)-272-4280, fax: (505)-272-6091.
    Affiliations
    Department of Neurosurgery, University of New Mexico Hospital (UNMH), 1 University New Mexico, MSC10 5615, Albuquerque, NM, 87131, USA

    Bowers Neurosurgical Frailty and Outcomes Data Science Lab, Albuquerque, NM 87131, USA
    Search for articles by this author
Published:February 15, 2023DOI:https://doi.org/10.1016/j.spinee.2023.02.004
      Type 2 odontoid fractures (T2OF), defined by fracture through base of dens, account for ∼50% odontoid fractures and usually result in cervical instability [
      • Tenny S
      • Varacallo M.
      Odontoid fractures.
      ]. There is lack of consensus regarding which patients are appropriate for nonoperative (external immobilization) versus operative (surgical fixation, multiple approaches) management [
      • Tenny S
      • Varacallo M.
      Odontoid fractures.
      ]. Many surgeons lean towards nonoperative management in elderly patients [
      • Tenny S
      • Varacallo M.
      Odontoid fractures.
      ]. However, nonunion rates with brace therapy increase significantly with age and some elderly patients poorly tolerate external immobilization therapy [
      • Tenny S
      • Varacallo M.
      Odontoid fractures.
      ]. Frailty is a measure of physiological reserve and valuable risk stratification tool in the preoperative setting. The Risk Analysis Index (RAI) is a robust index based on accumulation of deficits model of frailty [
      • Hall DE
      • Arya S
      • Schmid KK
      • Blaser C
      • Carlson MA
      • Bailey TL
      • et al.
      Development and initial validation of the risk analysis index for measuring frailty in surgical populations.
      ,
      • Arya S
      • Varley P
      • Youk A
      • Borrebach JD
      • Perez S
      • Massarweh NN
      • et al.
      Recalibration and External Validation of the Risk Analysis Index: a Surgical Frailty Assessment Tool.
      ]. However, the clinical utility of RAI in patients with T2OF is unclear [
      • Pazniokas J
      • Gandhi C
      • Theriault B
      • Schmidt M
      • Cole C
      • Al-Mufti F
      • et al.
      The immense heterogeneity of frailty in neurosurgery: a systematic literature review.
      ]. The aim of the present study was to analyze the prognostic significance of preoperative frailty, as measured by RAI, with 30-day mortality after surgical treatment of T2OF using the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database, 2015-2020.

      Keywords

      Abbreviations:

      ACS-NSQIP (American College of Surgeons National Surgical Quality Improvement Database), mFI (modified Frailty Index), RAI (Risk Analysis Index), T2OF (Type II Odontoid Fracture)
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