For instance, in 1997, an early report on the treatment of 47 osteoporotic compression
fractures with the new vertebroplasty technique [
[1]
] found that patients who had severe pain did well, incredibly well. In fact, 90% had
pain relief within 24 hours. In short order, another group reported “complete pain relief” in 78% of patients with osteoporotic compression fractures treated with
vertebroplasty [
[2]
]. Not to be outdone, a third group in 1998 reported “immediate … complete relief of symptoms” in 90% of 80 patients with osteoporosis
treated with vertebroplasty[
[3]
]. Onward and upward, an arms race for more and more fantastic results, no control
groups need apply.To read this article in full you will need to make a payment
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References
- Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects.AJNR Am J Neuroradiol. 1997; 18: 1897-1904
- Vertebroplasty: clinical experience and follow-up results.Bone. 1999; 25: 11S-15S
- Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications, and results.Radiol Clin North Am. 1998; 36: 533-546
- Vertebroplasty, first 1000 levels of a single center: evaluation of the outcomes and complications.AJNR Am J Neuroradiol. 2007; 28: 683-689
- Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy.Am J Med. 2003; 114: 257-265
- Percutaneous vertebroplasty compared to conservative treatment in patients with painful acute or subacute osteoporotic vertebral fractures: three-months follow-up in a clinical randomized study.Spine. 2009; 34: 1349-1354
- A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures.N Engl J Med. 2009; 361: 557-568
- A randomized trial of vertebroplasty for osteoporotic spinal fractures.N Engl J Med. 2009; 361: 569-579
- Trials of vertebroplasty for vertebral fractures.N Engl J Med. 2009; 361 (author reply 2099–2100): 2098
- Trials of vertebroplasty for vertebral fractures.N Engl J Med. 2009; 361 (author reply 2099–2100): 2097-2098
- Trials of vertebroplasty for vertebral fractures.N Engl J Med. 2009; 361 (author reply 2099–2100): 2098
- Vertebroplasty: effective or not?.Neurosurgery. 2009; 65: N14
- Trials of vertebroplasty for vertebral fractures.N Engl J Med. 2009; 361 (author reply 2099–2100): 2098-2099
- Balancing science and informed choice in decisions about vertebroplasty.N Engl J Med. 2009; 361 (6): 619-621
- Consternation and questions about two vertebroplasty trials.Cleve Clin J Med. 2010; 77: 12-16
- Vertebroplasty was not effective for painful osteoporotic vertebral fractures.Ann Intern Med. 2009; 151: JC6-9
- North American Spine Society. Newly released vertebroplasty randomized controlled trials: a tale of two trials.Spine J. 2010; 10: 238-240
- Vertebroplasty: when randomized placebo-controlled trial results clash with common belief.Spine J. 2010; 10: 241-243
Article info
Publication history
Accepted:
January 14,
2010
Received:
January 14,
2010
Footnotes
FDA device/drug status: approved.
Author disclosures: EJC (stock ownership, Simpirica, Bioassetts, Cytonics; private investment, Simpirica; consulting, Medtronic, Synthes; trips/travel, US Army; scientific advisory board, Intrinsic Orthopedics, Cytonics; other office, Bioassetts; grants, AO Foundation; fellowship support, Depuy Spine; other, orthopedic surgeon).
Identification
Copyright
© 2010 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
