The Spine Journal
Volume 10, Issue 7 , Pages 602-609 , July 2010

Restoration of compressive loading properties of lumbar discs with a nucleus implant—a finite element analysis study

  • Daniel G.T. Strange, MEng

      Affiliations

    • Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Kogarah NSW 2217, Sydney, Australia
    • Department of Engineering, Cambridge University, Cambridge CB2 1PZ, UK
    • ,
  • Sandie T. Fisher, BEngg

      Affiliations

    • Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Kogarah NSW 2217, Sydney, Australia
    • ,
  • Philip C. Boughton, PhD

      Affiliations

    • Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Kogarah NSW 2217, Sydney, Australia
    • ,
  • Thomas J. Kishen, DNB (Ortho)

      Affiliations

    • Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Kogarah NSW 2217, Sydney, Australia
    • ,
  • Ashish D. Diwan, MBBS, PhD

      Affiliations

    • Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, Kogarah NSW 2217, Sydney, Australia
    • Corresponding Author InformationCorresponding author. Spine Service, Department of Orthopaedic Surgery, St George Hospital, University of New South Wales, PO Box 541, Kogarah NSW 2217, Sydney, Australia. Tel.: (61) 2-9588-9622; fax: (61) 2-9588-9722.

References 

  1. Australian Institute of Health and Welfare. Arthritis and musculoskeletal conditions in Australia 2005. Canberra, Australia: Australian Institute of Health and Welfare; 2005;Catalogue No.: PHE67
  2. Atlas SJ, Nardin RA. Evaluation and treatment of low back pain: an evidence-based approach to clinical care. Muscle Nerve. 2003;27:265–284
  3. Bao QB, McCullen GM, Higham PA, et al. The artificial disc: theory, design and materials. Biomaterials. 1996;17:1157–1167
  4. Lehmann TR, Spratt KF, Tozzi JE, et al. Long-term follow-up of lower lumbar fusion patients. Spine. 1987;12:97–104
  5. Bertagnoli R, Karg A, Voigt S. Lumbar partial disc replacement. Orthop Clin North Am. 2005;36:341–347
  6. Bao QB, Yuan HA. New technologies in spine: nucleus replacement. Spine. 2002;27:1245–1247
  7. Loupasis GA, Stamos K, Katonis PG, et al. Seven- to 20-year outcome of lumbar discectomy. Spine. 1999;24:2313–2317
  8. Meakin JR. Replacing the nucleus pulposus of the intervertebral disk: prediction of suitable properties of a replacement material using finite element analysis. J Mater Sci Mater Med. 2001;12:207–213
  9. Meakin JR, Reid JE, Hukins DW. Replacing the nucleus pulposus of the intervertebral disc. Clin Biomech. 2001;16:560–565
  10. Yao J, Turteltaub SR, Ducheyne P. A three-dimensional nonlinear finite element analysis of the mechanical behavior of tissue engineered intervertebral discs under complex loads. Biomaterials. 2006;27:377–387
  11. Joshi AB. Mechanical behavior of the human lumbar intervertebral disc with polymeric hydrogel nucleus implant: an experimental and finite element study [PhD thesis]. Philadelphia, PA: Drexel University, 2004:183.
  12. Klara PM, Ray CD. Artificial nucleus replacement: clinical experience. Spine. 2002;27:1374–1377
  13. Sabet T, Ho R, Choi J, Diwan A. Kinematics of the motion segment are restored using a novel nuclear replacement device—a comparative study using kangaroo spine model. In: Proceedings of the 7th Annual Scientific Meeting of the Spine Arthroplasty Society; 2007 May; Berlin, Germany.
  14. Pavlov P. The status of nucleus replacement for degenerative disc disease. In: Proceedings of AO Spine Masters Course; 2008 Dec; Davos Switzerland.
  15. Noailly J, Lacroix D, Planell JA. Finite element study of a novel intervertebral disc substitute. Spine. 2005;30:2257–2264
  16. Natarajan RN, Andersson GB. The influence of lumbar disc height and cross-sectional area on the mechanical response of the disc to physiologic loading. Spine. 1999;24:1873–1881
  17. Guo LX, Teo EC. Influence prediction of injury and vibration on adjacent components of spine using finite element methods. J Spinal Disord Tech. 2006;19:118–124
  18. Sharma M, Langrana NA, Rodriguez J. Role of ligaments and facets in lumbar spinal stability. Spine. 1995;20:887–900
  19. Renner SM, Natarajan RN, Patwardhan AG, et al. Novel model to analyze the effect of a large compressive follower pre-load on range of motions in a lumbar spine. J Biomech. 2007;40:1326–1332
  20. Zhong ZC, Wei SH, Wang JP, et al. Finite element analysis of the lumbar spine with a new cage using a topology optimization method. Med Eng Phys. 2006;28:90–98
  21. Schmidt H, Heuer F, Simon U, et al. Application of a new calibration method for a three-dimensional finite element model of a human lumbar annulus fibrosus. Clin Biomech (Bristol, Avon). 2006;21:337–344
  22. Little JP, Adam CJ, Evans JH, et al. Nonlinear finite element analysis of anular lesions in the L4/5 intervertebral disc. J Biomech. 2007;40:2744–2751
  23. Shirazi-Adl A, Ahmed AM, Shrivastava SC. A finite element study of a lumbar motion segment subjected to pure sagittal plane moments. J Biomech. 1986;19:331–350
  24. Goel VK, Monroe BT, Gilbertson LG, Brinckmann P. Interlaminar shear stresses and laminae separation in a disc. Finite element analysis of the L3–L4 motion segment subjected to axial compressive loads. Spine. 1995;20:689–698
  25. Shirazi-Adl SA, Shrivastava SC, Ahmed AM. Stress analysis of the lumbar disc-body unit in compression. A three-dimensional nonlinear finite element study. Spine. 1984;9:120–134
  26. Miller JA, Schultz AB, Warwick DN, Spencer DL. Mechanical properties of lumbar spine motion segments under large loads. J Biomech. 1986;19:79–84
  27. Lin HS, Liu YK, Adams KH. Mechanical response of the lumbar intervertebral joint under physiological (complex) loading. J Bone Joint Surg Am. 1978;60:41–55
  28. Panjabi MM, Krag MH, Chung TQ. Effects of disc injury on mechanical behavior of the human spine. Spine. 1984;9:707–713
  29. Denoziere G, Ku DN. Biomechanical comparison between fusion of two vertebrae and implantation of an artificial intervertebral disc. J Biomech. 2006;39:766–775
  30. Koh CG, Kelly JM. Compression stiffness of bonded square layers of nearly incompressible material. Eng Struct. 1989;11:9–15
  31. Hanley EN, Shapiro DE. The development of low-back pain after excision of a lumbar disc. J Bone Joint Surg Am. 1989;71:719–721
  32. Spengler DM. Lumbar discectomy. Results with limited disc excision and selective foraminotomy. Spine. 1982;7:604–607
  33. Berry JL, Moran JM, Berg WS, Steffee AD. A morphometric study of human lumbar and selected thoracic vertebrae. Spine. 1987;12:362–365
  34. Gilad I, Nissan M. A study of vertebra and disc geometric relations of the human cervical and lumbar spine. Spine. 1986;11:154–157
  35. Lee KK, Teo EC. Effects of laminectomy and facetectomy on the stability of the lumbar motion segment. Med Eng Phys. 2004;26:183–192
  36. Brown T, Hansen RJ, Yorra AJ. Some mechanical tests on the lumbosacral spine with particular reference to the intervertebral discs; a preliminary report. J Bone Joint Surg Am. 1957;39:1135–1164
  37. Markolf KL, Morris JM. The structural components of the intervertebral disc. A study of their contributions to the ability of the disc to withstand compressive forces. J Bone Joint Surg Am. 1974;56:675–687
  38. Virgin WJ. Experimental investigations into the physical properties of the intervertebral disc. J Bone Joint Surg Br. 1951;33:607–611

 FDA device/drug status: not applicable.

 Author disclosures: DGTS (other relationships, Columna Pty Ltd); PCB (board of directors, Biometic Pty Ltd; research support: staff/materials, University of New South Wales; other relationships, Columna Pty Ltd); ADD (stock ownership, including options and warrants, Cellixe Pty Ltd; private investments, including venture capital, start-ups, Columna; consulting, Synthes Asia Pacific; trips/travel, Synthes; board of directors, Cellixe Pty Ltd; grants, Stryker Biotech; fellowship support, Stryker, Synthes).

 D.G.T. Strange and S.T. Fisher have performed sufficient work to be treated as equal first authors.

PII: S1529-9430(10)00311-6

doi: 10.1016/j.spinee.2010.04.015

The Spine Journal
Volume 10, Issue 7 , Pages 602-609 , July 2010

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