The Spine Journal
Volume 10, Issue 6 , Pages 486-496 , June 2010

Cryopreserved intervertebral disc with injected bone marrow–derived stromal cells: a feasibility study using organ culture

  • Samantha C.W. Chan, MPhil

      Affiliations

    • AO Research Institute, CH-7270 Davos Platz, Switzerland
    • Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong
    • ARTORG Center for Biomedical Engineering Research, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH-3014 Bern, Switzerland
    • ,
  • Benjamin Gantenbein-Ritter, PhD

      Affiliations

    • AO Research Institute, CH-7270 Davos Platz, Switzerland
    • ARTORG Center for Biomedical Engineering Research, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH-3014 Bern, Switzerland
    • Corresponding Author InformationCorresponding author. ARTORG Center for Biomedical Engineering Research, Institute for Surgical Technology and Biomechanics, University of Bern, Stauffacherstrasse 78, CH-3014 Bern, Switzerland. Tel.: (41) 31-6315926; fax: (41) 31-6315960.
    • ,
  • Victor Y.L. Leung, PhD

      Affiliations

    • Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong
    • ,
  • Danny Chan, PhD

      Affiliations

    • Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong
    • ,
  • Kenneth M.C. Cheung, MD

      Affiliations

    • Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong
    • ,
  • Keita Ito, ScD

      Affiliations

    • AO Research Institute, CH-7270 Davos Platz, Switzerland
    • Department of Biomedical Engineering, Eindhoven University of Technology, NL-5600MB, Eindhoven, The Netherlands

Received 29 January 2009 ,Revised 7 November 2009 ,Accepted 25 December 2009.

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 FDA device/drug status: not applicable.

 Author disclosures: KMCC (research support for staff and materials, Synthes).

 Samantha C.W. Chan and Benjamin Gantenbein-Ritter contributed equally to this work.

PII: S1529-9430(10)00003-3

doi: 10.1016/j.spinee.2009.12.019

The Spine Journal
Volume 10, Issue 6 , Pages 486-496 , June 2010

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