The Spine Journal
Volume 2, Issue 1 , Pages 76-80 , January 2002

Minimally invasive treatment of osteoporotic vertebral body compression fractures

  • Steven R Garfin, MD

      Affiliations

    • University of California, San Diego, Medical Center, Orthopaedics Department, 200 W. Arbor 8894 Drive, San Diego, CA 92103-8894, USA
    • Corresponding Author InformationCorresponding author. University of California, San Diego, Medical Center, Orthopaedics Department, 200 W. Arbor 8894 Drive, San Diego, CA 92103-8894, USA. Tel.: (619) 543-2542; fax: (619) 543-2540.(S.R. Garfin)
  • ,
  • Mark A Reilley, MD

      Affiliations

    • Berkeley Orthopedic Medical Group, Berkeley, CA USA

Received 8 November 2000 ,Accepted 12 October 2001.

References 

  1. Riggs BL, Melton LJ. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 1995;5055–5115.
  2. Cooper C, Atkinson EJ, Jacobsen SJ, O'Fallon WM, Melton LJ. Incidence of clinically diagnosed vertebral fractures (a population-based study in Rochester, Minnesota, 1985–1989). J Bone Mineral Res. 1993;7:221–227
  3. Cook DJ, Guyatt GH, Adachi JD, et al, and the Multicentre Vertebral Fracture Study Group. Quality of life issues in women with vertebral fractures due to osteoporosis. Arthr Rheum 1993;36:750–756.
  4. Silverman S. The clinical consequences of vertebral compression fracture. Bone. 1992;13:S27–S32
  5. Gold DT. The clinical impact of vertebral fractures. Quality of life in women with osteoporosis. Bone. 1996;18(suppl):185S–189S
  6. Ross PD, David JW, Epstein RS, Wasnich RD. Pain and disability associated with new vertebral fractures and other spinal conditions. J Clin Epidemiol. 1994;47:234–239
  7. Lyles KW, Gold DT, Shipp KM, Pieper DF, Martinez S, Mulhausen PL. Association of osteoporotic vertebral fractures with impaired functional status. Am J Med. 1993;94:595
  8. Nevitt MC, Ettinger B, Black DM, et al.  The association of radiographically detected vertebral fractures with back pain and function (a prospective study). Ann Intern Med. 1998;15:793–800
  9. Oleksik A, Lips P, Dawson A, et al.  Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res. 2000;15:1384–1392
  10. Leech JA, Dulberg C, Kellie S, Pattee L, Gay J. Relationship of lung function to severity of osteoporosis in women. Am Rev Respir Dis. 1990;141:68–71
  11. Schlaich C, Minne HW, Bruckner T, et al. Osteo Internat 1998;8,261–267.
  12. Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR. Vertebral fractures and mortality in older women (a prospective study. Study of Osteoporotic Fractures Research Group). Arch Intern Med. 1999;159:1215–1220
  13. Uthoff HK, Jawaroski ZF. Bone loss in response to long term immobilization. J Bone Joint Surg. 1978;60:420–429[Br]
  14. Convertino VA, Bloomfield SA, Greenleaf JF. An overview of the issues: physiological effects of bed rest and restricted physical activity. Med Sci Exerc 1997:187–190.
  15. Galibert . Note préliminaire sur le traitement des angiomes vertébraux par vertébroplastie acrylique percutanée. Neurochirurgie. 1987;33:166–167
  16. Lapras injection percutané de methyl-métacrylate dans le traitement de l'oestéoporose et ostélyse vertébrale grave . Ann Chir. 1987;43:371–375
  17. Persson BM, Ekelund L, Lovdahl R, Gunterberg B. Favourable results of acrylic cementation for giant cell tumors. Acta Orthop Scand. 1984;55:209
  18. Bini SA, Gill K, Johnston JO. Giant cell tumor of bone. Clin Orthop. 1995;321:245
  19. O'Donnell RJ, Springfield DS, Motwani HK, Ready JE, Gebhardt MC, Mankin HJ. Recurrence of giant cell tumors of long bones after curettage and packing with cement. J Bone Joint Surg. 1994;76A:1827
  20. Hayes WC, Myers ER. Biomechanical considerations of hip and spine fractures in osteoporotic bone. Instr Course Lect. 1997;46:431–438
  21. Tomeh AG, Mathis JM, Fenton DC, Levine AM, Belkoff SM. Biomechanical efficacy of unipedicular versus bipedicular vertebroplasty for the management of osteoporotic compression fractures. Spine. 1999;24:1772–1776
  22. Cotton A, Dewatre F, Cortet B, et al.  Percutaneous vertebroplasty for osteolytic metastases and myeloma (effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up). Radiology. 1996;200:525–530
  23. Cortet B, Cotton A, Boutry R, et al.  Percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures (an open prospective study). J Rheum. 1999;26:222–228
  24. Weill A, Chiras J, Simon JM, Rose M, Sola-Martinez T, Enkaoua E. Spinal metastases (indications for and results of percutaneous injection of surgical cement). Radiology. 1996;199:241–247
  25. Jensen ME, Evans AJ, Mathis JM, Kallmes DF, Cloft HJ, Dion JE. Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures (technical aspects). Am J Neurorad. 1997;18,1897–1904:
  26. Deramond H, Depriester C, Galibert P, Le Gars D. Percutaneous vertebroplasty with polymethylmethacrylate. Technique, indications and results. Radiol Clin N Am 1998;36,533–546.
  27. Padovani B, Kasriel O, Brunner P, Peretti-Viton P. Pulmonary embolism caused by acrylic cement (a rare complication of percutaneous vertebroplasty). Am J Neurorad. 1999;20:375–377
  28. Chiras J. Percutaneous vertebral surgery. Techniques and indications. J Neurorad. 1997;24:45–52
  29. Presentation: American Academy of Orthopaedic Surgeons, 68th Annual Meeting. Early Outcomes in the Minimally Invasive Reduction and Fixation of Compression Fractures. San Francisco, CA, 2001.
  30. Lieberman I, Dudeney S. Initial outcome and efficacy of kyphoplasty in the treatment of painful osteoporotic vertebral compression fractures. Spine. 2001;126:1631–1638

 FDA device/drug status: Approved for this indication (KyphX inflatable balloon tamp)

☆☆ FDA device/drug status: Not approved for this indication (PMMA)

 SRG and MAR acknowledges a financial relationship (Kyphon, Inc.) that may indirectly relate to the subject of this manuscript.

PII: S1529-9430(01)00166-8

The Spine Journal
Volume 2, Issue 1 , Pages 76-80 , January 2002